INTENSITY OF FREE RADICAL PROCESSES IN RAT SKELETAL MUSCLES UNDER THE CONDITIONS OF DIFFERENT DIETARY SUPPLY WITH NUTRIENTS

The intensity of free-radical processes in the skeletal muscles rats at different dietary supply with protein and sucrose was studied. It has been established that most pronounced intensification free radical mitochondria is found animals kept on a low-protein/ high-sucrose diet. In particular, generation superoxide anion-radical increases more than 5,3-fold hydroxyl 3,2-fold compared control, 14,3-fold increase carbonyl derivatives levels, also decreases by three times SH-groups levels against background 1,7-fold decrease catalase activity. shown excessive consumption critical factor influencing muscle mitochondria. detected changes can be considered as prerequisites for dysfunction under conditions nutrient imbalance.